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What are possible drug interactions with Levitra?

Below you will find some information excerpted from the FDA-approved package insert for Levitra. However, you should discuss with your doctor and pharmacist any medications you are currently taking or any health problems you have, since this list may not be complete or up-to-date.  You should also download and read the entire insert in detail before taking Levitra. Download the insert from the FDA web site: http://www.fda.gov/cder/foi/label/2003/021400lbl.pdf.

Do not take LEVITRA if you:

• take any medicines called "nitrates" (See "What important information should you know about LEVITRA?"). Nitrates are commonly used to treat angina. Angina is a symptom of heart disease and can cause pain in your chest, jaw, or down your arm.
  
  Medicines called nitrates include nitroglycerin that is found in tablets, sprays, ointments, pastes, or patches. Nitrates can also be found in other medicines such as isosorbide dinitrate or isosorbide mononitrate. Some recreational drugs called "poppers" also contain nitrates, such as amyl nitrate and butyl nitrate. Do not use LEVITRA if you are using these drugs. Ask your doctor or pharmacist if you are not sure if any of your medicines are nitrates.
   

• use recreational drugs called "poppers" like amyl nitrate and butyl nitrate.
   

• take medicines called "alpha-blockers." Alpha-blockers are sometimes prescribed for prostate problems or high blood pressure. If LEVITRA is taken with alpha-blockers, your blood pressure could suddenly drop to an unsafe level. You could get dizzy and faint.
   

• you have been told by your healthcare provider to not have sexual activity because of health problems. Sexual activity can put an extra strain on your heart, especially if your heart is already weak from a heart attack or heart disease.
   

• are allergic to LEVITRA or any of its ingredients. The active ingredient in LEVITRA is called vardenafil.

  • Active Ingredient: vardenafil hydrochloride

  • Inactive Ingredients: microcrystalline cellulose, crospovidone, colloidal silicon dioxide, magnesium stearate, hypromellose, polyethylene glycol, titanium dioxide, yellow ferric oxide, and red ferric oxide.

Before taking LEVITRA, tell your doctor about all your medical problems, including if you:

have heart problems such as angina, heart failure, irregular heartbeats, or have had a heart attack. Ask your doctor if it is safe for you to have sexual activity.

• have low blood pressure or have high blood pressure that is not controlled

• have had a stroke

• or any family members have a rare heart condition known as prolongation of the QT interval (long QT syndrome)

• have liver problems

• have kidney problems and require dialysis

• have retinitis pigmentosa, a rare genetic (runs in families) eye disease

• have stomach ulcers

• have a bleeding problem

• have a deformed penis shape or Peyronie's disease

• have had an erection that lasted more than 4 hours

• have blood cell problems such as sickle cell anemia, multiple myeloma, or leukemia

Can other medications affect LEVITRA?

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. LEVITRA and other medicines may affect each other. Always check with your doctor before starting or stopping any medicines. Especially tell your doctor if you take any of the following:

medicines called nitrates (See "What important information should you know about LEVITRA?")
medicines called alpha-blockers. These include Hytrin® (terazosin HCl), Flomax® (tamsulosin HCl), Cardura® (doxazosin mesylate), Minipress® (prazosin HCl) or Uroxatral® (alfuzosin HCl).
medicines that treat abnormal heartbeat. These include quinidine, procainamide, amiodarone and sotalol.
ritonavir (Norvir®) or indinavir sulfate (Crixivan®)
ketoconazole or itraconazole (such as Nizoral® or Sporanox®)
erythromycin
other medicines or treatments for ED